KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
0.91
Human Site:
S616
Identified Species:
2
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S616
Q
Q
Y
A
D
L
L
S
H
D
Q
L
L
T
E
Chimpanzee
Pan troglodytes
XP_526066
929
104074
E377
F
L
H
F
E
E
E
E
I
T
F
A
P
T
Y
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
Q636
E
P
L
L
R
V
D
Q
L
N
L
E
R
E
K
Dog
Lupus familis
XP_542327
1264
138869
Q642
E
P
L
L
R
V
D
Q
L
N
L
E
R
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
A619
Q
Q
Y
S
D
L
L
A
H
D
Q
L
L
L
E
Rat
Rattus norvegicus
P97573
1190
133575
A618
Q
Q
Y
S
D
L
L
A
H
D
Q
L
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
I467
P
H
F
S
G
S
N
I
T
E
I
I
N
P
N
Chicken
Gallus gallus
XP_422567
1182
133482
A615
Q
Q
Y
P
E
L
L
A
F
D
Q
L
L
I
E
Frog
Xenopus laevis
Q6P4S2
1019
115278
T467
I
H
S
L
R
E
I
T
S
V
E
Y
K
V
I
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
Q620
D
P
L
L
K
V
D
Q
L
N
L
E
R
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
Q618
E
V
L
F
N
H
D
Q
L
K
I
E
K
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
6.6
0
0
N.A.
80
80
N.A.
0
66.6
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
26.6
26.6
N.A.
93.3
93.3
N.A.
26.6
80
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
28
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
28
0
37
0
0
37
0
0
0
10
0
% D
% Glu:
28
0
0
0
19
19
10
10
0
10
10
37
0
28
37
% E
% Phe:
10
0
10
19
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
19
10
0
0
10
0
0
28
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
10
10
0
19
10
0
10
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
10
0
0
19
0
28
% K
% Leu:
0
10
37
37
0
37
37
0
37
0
28
37
37
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
28
0
0
10
0
10
% N
% Pro:
10
28
0
10
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
37
37
0
0
0
0
0
37
0
0
37
0
0
0
10
% Q
% Arg:
0
0
0
0
28
0
0
0
0
0
0
0
28
0
0
% R
% Ser:
0
0
10
28
0
10
0
10
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
10
0
0
0
19
0
% T
% Val:
0
10
0
0
0
28
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
37
0
0
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _